Can new drugs like Ravrvxaban replace warfarin?

Warfarin is considered as an effective anticoagulant, but some of its weaknesses. Your doctor will need to have blood tests for coagulation such as INR when taking this medication regularly to prevent accidental bleeding, such as bleeding into the brain or even bleeding into the stomach. Warfarin, due to interactions with other medicines or foods, can challenge everyday life and make changes in the diet. Newer alternatives to warfarin have advantages and disadvantages compared to warfarin.

What other options for warfarin exist?
Currently, newer drugs are available as alternatives to warfarin. Some of these drugs are edible drugs, some subcutaneously. Oral medicines include Apixaban, Dabigatran, Edoxaban and Rivaroxaban. Injectable drugs include Dalteparin, Enoxaparin, Fondaparinux.

Ravaroox (Xarelto)
The use of this drug is for treating DVT, pulmonary embolism, reducing the recurrence of these two diseases, as well as prevention of clots resulting from knee replacement surgery and pelvic surgery and reducing the risk of stroke.

How do they work?
Like warfarin, these drugs prevent blood clots. They also reduce the risk of other clots. However, the way the new drugs are used in the body is different from the functions of the warfarin drug. They affect a different section of the process of clotting. This difference often makes new drugs more suitable for use.

Advantages
Since the use of these drugs begins, less time is spent to reach the peak of efficacy.
During the treatment, there is a need for less blood tests to check for anticoagulants in the blood.
Their effectiveness does not interfere with the diet.
Disadvantages
Probably more expensive than warfarin.
These drug options may increase the risk of bleeding for some people.
Due to the fact that they have not been studied as much as warfarin, these drugs are not fully known for their long-term effects on the body.
Should you change the drug Warfarin?
There are few advantages and disadvantages of warfarin for new medications, and there is no permission to arbitrarily change the drug.

For example, if kidney failure is present, the doctor will likely prescribe warfarin, otherwise, based on the physical condition, the doctor will be the final decision maker.

References:

  1. https://www.rxlist.com/script/main/art.asp?articlekey=170265
  2. https://www.healthline.com/health/dvt/warfarin-alternatives

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Fatemeh Ghorbani

Fatemeh Ghorbani

فاطمه قربانی هستم، لیسانس ژنتیک، به علوم نوین پزشکی و ایمونولوژی علاقمندم. از شما دوست گرامی بخاطر مطالعه این مقاله و همچنین مجموعه تریتا بخاطر فرصت انتشار مطالبم در راستای کمک به ارتقای دانش کمال تشکر دارم. شاد باشید و سلامت

my name is Fatemeh Ghorbani, I have a B.S in genetics and interested in immunology and medical science. I believe that, even into the smallest acts, should be put our heart, mind and soul. Thank you for reading my article