Hepatitis B tests and test results

Hepatitis B is a liver infection caused by hepatitis B virus (HBV). Hepatitis B blood tests detect viral proteins (antigens) and antibodies produced in response to infection, or detect and evaluate the genetic material (DNA) of the virus. The test result pattern can identify a person who has an active current infection, or has previously been exposed to HBV or immunized as a result of vaccination.

 

Read more:
What do you know about hepatitis B and its symptoms?

 

The course of HBV infections may range from a mild form that lasts only a few weeks to chronic illness that persists for many years to come. Sometimes chronic HBV can lead to more serious complications such as cirrhosis or liver cancer. Some of the stages or types of hepatitis B include:

Acute infection: There are common signs and symptoms with positive HBV testing

Chronic infection: Continuous infection with the virus detected by laboratory tests and associated with inflammation of the liver.

Carrier status: Continuous infection (determined by HBV tests) but no liver inflammation

(The carrier is someone who may sound healthy but who has the virus and can potentially infect others)

Eliminated or disabled infection: There is no evidence of infection. Viral antigens and DNA tests are negative and there are no signs or symptoms of liver inflammation (although in many cases the virus is inactive in the liver and can be potentially reactivated)

The recurrence of HBV infection (detected by HBV tests) is associated with liver injury in a person who carries or has an inactive infection. This condition often occurs in people with chemotherapy for cancer or those who receive immunosuppressive drugs for the treatment of autoimmune diseases or organ transplants. It can also occur during treatment for hepatitis HCV (C) in people who have been exposed to HBV in the past.

What is the test for hepatitis B?
To determine if acute symptoms and symptoms, such as jaundice, fever, and fatigue, are due to hepatitis B infection.
To diagnose chronic hepatitis
To control chronic hepatitis B infection and its treatment
To detect a previous infection, hepatitis B has been resolved in someone who has already been in danger. Or hepatitis C and is under treatment.
Some of the secondary reasons for this test are: the incidence of hepatitis B infection in people at risk or in blood donors, to determine whether someone is carrying out, to diagnose an infection, or to determine whether the immunity required by injection Vaccination has been created or not.
A summary of the cases in the early studies of hepatitis B include:
(HBsAG) detects surface antigens of hepatitis B, or viral viral proteins.
(anti-HBs) detects surface hepatitis antibodies, which produce these antibodies in response to surface antigens of hepatitis.
(B anti-HBc, IgM, IgG) detects antibodies against the entire hepatitis virus.
(anti-HBc, IgM) detects antibodies against the hepatitis B virus nucleus.
Of course, these four tests will be tested at the initial stage and if there are other problems, the doctor will prescribe other hepatitis tests in line with these tests.

The failure of the four early tests indicates that there is no current or previous infection. Of course, it should be noted that in this case there is no immunity for this virus, so it should be done on vaccination.
If only four of the above tests are positive (anti-HBs) alone, there is no problem with the infection and the immune system is well suited to the virus.
If tests two and three are positive, the infection is gone, but the probability of the virus being hidden is also due to the suppression of the immune system.
If tests 1 and 4 are positive, it indicates an active infection. Usually associated with symptoms. It is contagious. It can become chronic.
If tests 3 and 4 are positive, the active infection has been eliminated.
If tests 1 and 3 are positive, the active infection is chronic and there is a risk of liver damage. The possibility of a latent infection is not expected at this stage.
This test does not require any special training. Even if you feel that you do not have any clinical symptoms but are exposed to one of the ways to get this virus, it's best to have a simple blood test to find out. Even if you have been infected with this virus, treatment is very effective in the treatment process and minimizes the risk of liver damage.

The blood bank carries out all tests for the blood virus on blood donors, so blood donors are not worried.

Note that if you are not exposed to the virus and do not remember your last vaccination, you will probably receive a dose of immunoglobulin hepatitis B (HBIG) within 24 hours and usually the first dose of the hepatitis B vaccine. They will help you to control the virus.

You can simply use the membership in Trita and enter the user's area of ​​the Intelligent Physician System, you will also be able to test your Hepatitis Trita in Trita and interpret the values ​​in your test without a doctor. Please refer to the Blood Tests section at the beginning of the study.

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References:

  1. https://labtestsonline.org/tests/hepatitis-b-testing#

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Fatemeh Ghorbani

Fatemeh Ghorbani

فاطمه قربانی هستم، لیسانس ژنتیک، به علوم نوین پزشکی و ایمونولوژی علاقمندم. از شما دوست گرامی بخاطر مطالعه این مقاله و همچنین مجموعه تریتا بخاطر فرصت انتشار مطالبم در راستای کمک به ارتقای دانش کمال تشکر دارم. شاد باشید و سلامت

my name is Fatemeh Ghorbani, I have a B.S in genetics and interested in immunology and medical science. I believe that, even into the smallest acts, should be put our heart, mind and soul. Thank you for reading my article