Parkinson Parkinson Disease, Symptoms, Causes, and Treatments

Parkinson Parkinson Disease, Symptoms, Causes, and Treatments
Parkinson's disease is an advanced nerve dysfunction that is accompanied by tremors. Symptoms of the disease begin gradually. Sometimes it starts with a sudden sudden thrill in one hand. In the early stages of Parkinson's disease, there is a slight disorder in speech.

Symptoms of Parkinson's disease improve over time. Although Parkinson's disease can not be treated, medications can significantly improve your symptoms. Sometimes a doctor recommends surgery for surgery.

 

Familiarity with Parkinson's Disease Symptoms
The symptoms and symptoms of Parkinson's disease are different for everyone. Early symptoms may be mild.

Vibration: Start vibrations on one side of the body, usually starting at the fingertips.
Relaxation (Bradykinzia): As time passes, Parkinson's disease may slow your movement, these people can not do their normal tasks properly. They can not even walk right and drop their feet on the ground.
Muscle stiffening: Muscle stiffness may occur in any part of the body. The muscles become stiff and painful and limit your range of motion.
Body imbalance: Other symptoms of the disease are imbalance in the body.
Loss of body movements: This disease may decrease the ability of the body to subconscious movements. Including blinking, smiling or swinging your hands while walking.
Speech changes: You may experience speech impairment. You may not even be able to correctly say a few small sentences.


Causes of Parkinson's Disease
In Parkinson's disease, some neurons (neurons) in the brain gradually disappear. Many of these symptoms are due to the loss of neurons that a chemical messenger generates in your brain called dopamine. When the level of dopamine decreases, it causes abnormal brain activity and this causes Parkinson's disease.

The cause of Parkinson's disease is unknown, but it seems that several factors, including:

1- Genetics
Experts have identified certain genetic mutations in the disease that cause Parkinson's disease. These genetic mutations are very rare and unusual.

2. Environmental stimuli
Exposure to certain toxins or cigarette smoke and air pollution increases the risk of Parkinson's disease. The researchers also noted that there are many changes in the brain of people with Parkinson's disease, although it is unclear why these changes occur. These changes include:

Lewy bodies: Lewy bodies are protein beads that extend into nerve cells in nerve patients such as Parkinson's. These microscopic grains are clearly identifiable during the biopsy of the cerebrospinal fluid.
Alpha-synuclein alpha: Scientists believe that the natural and extensive protein called alpha sinuclining, or alpha-synuclein protein, has many effects on the body. Research on mice showed that alpha protein, if taken naturally in a naturally occurring area, would cause Parkinson's disease.
risk factors
The risk factors for Parkinson's disease are:

Age: Rarely, Parkinson's disease is experienced by young people. The usual age of this disease is usually over 60 years.
Heredity: Heredity and family history increases the chances of getting the disease.
Sex: Men are more likely to develop Parkinson's than men.
Exposure to poisons: Exposure to herbicides and pesticides may slightly increase the risk of Parkinson's disease.
Side effects of Parkinson's disease
Intellectual and psychological problems
Depression and emotional changes
Fear and anxiety and loss of motivation
Problems in swallowing (blockage of the throat)
Problems in chewing and eating
Changes in the face, jaw and mouth muscles (sometimes it can lead to choking and shortness of breath)
Sleep disorders (stay awake during the night and sleep during the day)
Administrative problems and impaired bladder function
Severe constipation
Severe hypertension (may cause very chronic dizziness)
Impaired sense of smell
fatigue
Severe pain
Sexual dysfunction (loss of libido)


Diagnosis of Parkinson's Disease
Medical history
Physical examination
Dopamine Scan (DAT)
blood test
Imaging MRI, CT
Brain Scan
In addition to your examination, your doctor may prescribe carbidopa levodopa (Ritary, Sinemet). To diagnose the disease, you will be given a dose sufficient to diagnose the disease.

Parkinson's treatment
Parkinson's disease can not be treated, but medications can help control your symptoms; in some cases, surgery may be recommended. Your doctor may also suggest lifestyle changes, especially aerobic exercise. In some cases, physical therapy that focuses on balance and stretching is also important. Spoken language pathologist may help improve speech problems.

1- Introduction of Parkinson's Drugs
Carbidopa-levodopa: (Carbidopa levodopa) is the most effective treatment for Parkinson's disease. This natural chemical is transferred to your brain and produces dopamine.
Lodosyn: This medication is combined with levodopa double carb and reduces nausea caused by it.
Dopamine Agonists: Unlike levodopa, dopamine agonists do not alter dopamine. Instead, they increase the effects of dopamine in your brain. Dopamine agonists include Pramipexole Mirapex, Ropinilol (Requip) and Rutigotine (Neupro, as a patch given). Apomorphine Apokyn is a short-acting injectable dopamine agonist that is used fast to expedite. The complications of dopamine agonists include anxiety and delusion and severe sleepiness.
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References:

  1. https://www.mayoclinic.org/diseases-conditions/parkinsons-disease/symptoms-causes/syc-20376055
  2. https://www.webmd.com/parkinsons-disease/default.htm

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Masoome Rahi

Masoome Rahi

معصومه راهی هستم،کارشناس مترجمی زبان انگلیسی،مدت ۴ سال سابقه ترجمه دارم و اعتقاد دارم تنها راه رسیدن به موفقیت انجام کاریست که بهش علاقه داری

I m masoomeh rahi and im bachelors degree in english translation.i translated in 4 years and i believe that the only way to success is to love what to do