Liver function tests (LFT)

The liver performs various tasks that are important for the health of the body. From food decomposition to blood purification, protein production and energy storage are a small part of these tasks. The slightest changes in the proper functioning of this organ will cause symptoms that will force you to test liver function tests.

The liver function test is just a test title for several distinct sections. Several tests that measure the amounts of proteins and enzymes in the body will be measured. Examining some of these values ​​in the experiment is only possible if there is a risk of liver injury or a specific disease.

When is it necessary to perform liver function tests?
This test is done when you have liver problems such as hepatitis or diseases that cause liver swelling. Some liver problems cause symptoms that double the need for this test. Symptoms such as:

Darkening of the urine color or change in stool color
Being eaten
Abdominal swelling
Weakness or feeling tired
Jaundice of the eyes and skin (jaundice)
Skin rash
Of course, sometimes, the person does not show any symptoms during his or her life, and the doctor will probably ask for these tests by examining some of the conditions in the lifestyle and physical conditions. These conditions include:

People with high alcohol intake
People with a history of family history of liver disease
Overweight, especially in people with diabetes or with cardiovascular disease
Drug use increases the risk of liver damage
Types of tests available in liver function tests
The liver function test includes several separate names that we briefly describe for each one:

1- ALT test:
This test is an abbreviation for the Alanine aminotransferase enzyme. An enzyme found in the liver and showing higher levels in liver damage.

2- ALP Test:
The test is called alkaline phosphatase, which is present in the liver, bile ducts and bones. Damage or liver disease, blockage of bile ducts and bone diseases will increase the amount of this component in the test.

3. AST test:
Aspartate transaminase is an enzyme present in the liver whose high levels are a sign of liver disease.

4. GGT Test:
A high level of gamma glutamyltransferase enzymes can indicate liver damage or bile ducts.

5- LD test:
The lactate dehydrogenase enzyme is another enzyme that increases its levels of disease or liver damage. But other conditions can increase the level of this substance in the blood. For example, physicians use it to investigate the cause of heart pain and the risk of heart attacks.

6. Bilirubin Test:
Bilirubin is caused by the breakdown of red blood cells. The liver clears the bilirubins. If the level of bilirubin is high, there is a problem called jaundice in a person that is likely to be due to liver damage.

7. PT Test:
The proton time is a test that evaluates the time of blood clotting. The high level of this component is either a sign of liver damage, or in people taking anticoagulants.

8. Albumin test and all blood proteins:
Your liver is the builder of two major types of proteins called albumin and globin. The low levels of these two components are signs of injury or liver disease.

Review the results of the liver function test
Here is a look at the results of the test for one of the conditions and liver diseases called acute hepatic injury. Acute liver damage occurs due to drug use, infection, toxins, and the like. In this case, the amount of bilirubin is normal or increased, usually after increasing ALT and AST. The levels of ALT and AST usually show a sharp increase, and ALT is usually higher than AST. GGT and ALP values ​​are normal in these conditions or with only a slight increase. Albumin and PT values ​​are usually normal in these conditions.

Conditions that can affect the outcome of liver tests
The presence of abnormal amounts as a result of the test should not be a criterion for detection alone, since the following conditions can affect the outcome of the test, including:

Shock
Burn
Severe infections
Muscle damage
Dehydration
Pancreatitis or pancreatic inflammation
Muscle damage
Blood hemolysis
Pregnancy
This test does not require any special training and you can easily test it.

You can simply use the membership in Trita and enter the user's area of ​​the Intelligent Physician System, you will also be able to record your liver tests in Trita and interpret your test values ​​without the need for a physician. Please check the blood tests section after you arrive.

References:

  1. https://www.webmd.com/hepatitis/liver-function-test-lft#1
  2. https://www.labtestsonline.org.au/learning/test-index/liver-function

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Fatemeh Ghorbani

Fatemeh Ghorbani

فاطمه قربانی هستم، لیسانس ژنتیک، به علوم نوین پزشکی و ایمونولوژی علاقمندم. از شما دوست گرامی بخاطر مطالعه این مقاله و همچنین مجموعه تریتا بخاطر فرصت انتشار مطالبم در راستای کمک به ارتقای دانش کمال تشکر دارم. شاد باشید و سلامت

my name is Fatemeh Ghorbani, I have a B.S in genetics and interested in immunology and medical science. I believe that, even into the smallest acts, should be put our heart, mind and soul. Thank you for reading my article