When are skin rashes of sweet syndrome?

Sweet Syndrome is a rare skin disorder. Its main symptoms are fever and painful skin lesions that appear mostly on the arms, neck, head and trunk.

The most common treatment for sweet syndrome is corticosteroids such as prednisone. Symptoms often disappear a few days after the onset of treatment, but relapses are common.

signs
The main symptoms of sweet syndrome are the appearance of small red seeds on the arms, neck, head and trunk. They often appear suddenly after a fever or upper respiratory tract infection. These seeds quickly grow larger and reach about 2.5 cm or more in painful clusters.

When to see a doctor
If you have a painful red rash that gets bigger quickly, see your doctor for appropriate treatment.

reasons
In most cases, the cause of the syndrome is not known. Sweet Syndrome is sometimes associated with cancer, and is often associated with leukemia. Sometimes this disorder may be associated with a solid tumor such as breast or colon cancer. Sweet Syndrome may also occur as a reaction to a drug. Most drugs that produce white blood cells are exacerbated by these conditions.

risk factors
Sweet syndrome is not common, but certain factors that can increase the risk of infection include:

Sex
In general, women are more likely to have these conditions than men.

Age
Although the elderly and even the infants may develop a syndrome, the disease occurs mostly in people between 30 and 60 years of age.

Cancer
Other health problems. Sweet Syndrome may occur following an upper respiratory tract infection, and many people report flu symptoms before they appear. There is also a chance that it will occur with inflammatory bowel disease.

Pregnancy
Some women experience sweat syndrome during pregnancy.

medical allergy
Drugs associated with the syndrome include Azathioprine (Azasan, Imuran), granulocyte coker stimulus factor, specific antibiotics and some non-steroidal anti-inflammatory drugs.

Diagnosis
A dermatologist can diagnose sweet syndrome just by looking at the lesions. But it's likely to prescribe specific tests to reject conditions that have similar symptoms, and these tests include:

blood test
A blood sample may be taken to check the amount of white blood cells as well as blood disorders.

Skin biopsy
The doctor may cut a small fraction of the damaged tissue for testing under a microscope. The tissue is analyzed to determine if there are any main characteristics of the sweet syndrome.

Treatment
Skin rashes of the sweet syndrome may disappear without treatment. But medications can dramatically improve the process. The most commonly used drugs for sweet syndrome are corticosteroids that are found in many different types, including:

Oral corticosteroids
These pills, like prednisone, work well but affect your whole body.

If the number of lesions is more than a few, it is likely that taking corticosteroids will be necessary. Long-term consumption can cause side effects such as weight gain, insomnia and bone weakness.

Cream or ointment
These materials can only be used on a part of the skin.

Injection
Another option is to inject a small amount of corticosteroid directly into any lesion. This may be less possible for people with a large number of lesions. Sometimes other drugs are prescribed for sweet syndrome, and are usually used in people who are not able to take long-term corticosteroids. Some common corticosteroid medications include:

Dapson
Potassium iodide
Colchicine (Colcrys, Mitigare)

References:

  1. https://www.mayoclinic.org/diseases-conditions/sweets-syndrome/symptoms-causes/syc-20351117

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Fatemeh Ghorbani

Fatemeh Ghorbani

فاطمه قربانی هستم، لیسانس ژنتیک، به علوم نوین پزشکی و ایمونولوژی علاقمندم. از شما دوست گرامی بخاطر مطالعه این مقاله و همچنین مجموعه تریتا بخاطر فرصت انتشار مطالبم در راستای کمک به ارتقای دانش کمال تشکر دارم. شاد باشید و سلامت

my name is Fatemeh Ghorbani, I have a B.S in genetics and interested in immunology and medical science. I believe that, even into the smallest acts, should be put our heart, mind and soul. Thank you for reading my article